House Republicans announce major shakeup for key committee that oversees energy, health, technology policy

FIRST ON FOX: House Republican leaders announced a shakeup of the structure of the House Energy and Commerce Committee, a key panel that oversees a wide-range of energy, health care and technology-related issues.

Rep. Cathy McMorris Rodgers, R-Wash., who recently assumed the role as chair of the Energy and Commerce Committee, announced the change Wednesday, saying the panel would be “reoriented” to help it succeed at its mission. The shakeup mainly impacts the responsibilities of the panel’s subcommittees and shifts how the committee will be equipped with addressing its priorities.

“For 227 years, the Energy and Commerce Committee has led on solutions to keep the promise of America, where we have lifted more people out of poverty and led the world in raising people’s standard of living,” McMorris Rodgers told Fox News Digital in a statement. “This Congress, Republicans will continue to honor the committee’s rich history to improve people’s lives and ensure America leads a new era of innovation and entrepreneurship.” 

“That is why we are reorienting our subcommittees to ensure our work tackles the greatest challenges and most important priorities of the day, including lowering energy costs, beating China, and building a more secure future,” she continued.

REPUBLICANS’ SPR BILL LEAVES DEMOCRATS SQUIRMING OVER OIL LEASING: ‘IT’S THE PROCESS OF BALANCE’

House Energy and Commerce Committee Chairwoman Cathy McMorris Rodgers, R-Wash., speaks during a hearing on Capitol Hill in 2019.

House Energy and Commerce Committee Chairwoman Cathy McMorris Rodgers, R-Wash., speaks during a hearing on Capitol Hill in 2019.
(Zach Gibson/Getty Images)

Under the changes, the Energy Subcommittee will change to the Energy, Climate, and Grid Security Subcommittee; the Environment and Climate Change Subcommittee will switch to the Environment, Manufacturing, and Critical Minerals Subcommittee; and the Consumer Protection and Commerce Subcommittee will now be the Innovation, Data, and Commerce Subcommittee.

The Communications and Technology, Health and Oversight Subcommittees will remain unchanged.

REPUBLICAN LEADERS PROMISE AGGRESSIVE ENERGY-RELATED OVERSIGHT: ‘WE INTEND TO PULL BACK THE CURTAIN’

Overall, the alterations to the committee’s structure highlight how committee Republicans, who have promised to aggressively tackle hot-button issues on energy, climate, Big Tech and health, aim to address those key issues. 

Under the changes, the newly-named Energy, Climate, and Grid Security Subcommittee will notably have jurisdiction of climate change issues. Republicans have argued that solutions to climate change go hand-in-hand with boosting energy security

House Energy and Natural Resources ranking member Frank Pallone, D-N.J., speaks during a hearing on April 6, 2022.

House Energy and Natural Resources ranking member Frank Pallone, D-N.J., speaks during a hearing on April 6, 2022.
(Al Drago/Bloomberg via Getty Images)

The Environment, Manufacturing, and Critical Minerals Subcommittee will seek to pursue policies that broadly reduce reliance on Chinese supply chains, including critical mineral supply chains which are vital for green energy development. The name change comes as Republicans continue to seek permitting reform that would remove regulations they say hamper domestic manufacturing and mining.

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And the Innovation, Data, and Commerce Subcommittee is set to seek solutions to the vulnerability of Americans’ data to abuse from Big Tech companies and the Chinese government.

“Trust and confidence in representative government is broken,” McMorris Rodgers said earlier this month. “Accountability in federal agencies is nonexistent, so the Biden administration is pushing radical policies to please its political allies. And the American people are paying the price for it — at the pump, at the grocery store and at the doctor’s office.

“The Energy and Commerce Committee is at the center of solving the most important issues facing hardworking Americans — lowering costs, promoting free speech and preserving free markets.”

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Exclusive: Goldman Sachs says even a near-default on US debt could spark a recession and market mayhem


New York
CNN
 — 

A full-blown debt ceiling crisis has the potential to stop the US economy in its tracks, according to the top economist at Goldman Sachs.

“If there were any doubt about the US government’s ability or willingness to make interest and principal payments on time, that could have very, very adverse consequences,” Jan Hatzius, the chief economist at Goldman Sachs, told CNN in an interview.

The United States hit the debt ceiling last week, forcing Treasury Secretary Janet Yellen to make accounting maneuvers to avoid breaching that $31 trillion borrowing limit.

If Congress fails to lift the debt ceiling in time, Hatzius said investors will worry there is a chance of a missed payment on US Treasuries – which are “maybe the most important asset in the global economy.”

Unlike many of its peers on Wall Street, Goldman Sachs is relatively bullish on the US economy, with Hatzius telling CNN that America will likely avoid a recession through the 2024 presidential election.

However, a debt ceiling crisis is a key risk to that optimistic outlook.

Asked if a default or even a near default could cause a recession, Hatzius said yes.

“That is the worry: That you get turmoil in financial markets, a big tightening in financial conditions and that adds to downward pressure on economic activity,” he said. “That is certainly the worry. It’s not our expectation.”

Economists and US officials have previously warned of dire consequences if the federal government exhausts the extraordinary measures being used to avoid a default.

Yellen told CNN’s Christiane Amanpour last week that a “global financial crisis” could result if Washington fails to make payments. Economist Mark Zandi once described an actual default as “financial Armageddon.”

History shows Congress eventually reaches a deal to raise the debt ceiling, although there have been close calls in the past. In 2011, the United States had its perfect AAA credit rating downgraded by S&P Global Ratings as lawmakers struggled to find a compromise. That episode helped set off turbulence on Wall Street and dented business confidence.

Leaders on Wall Street and Washington have warned that this debt ceiling negotiation could be especially challenging.

The historic dysfunction that preceded House Speaker Kevin McCarthy’s election earlier this month underscored how hard it will be to get contentious legislation through the House of Representative. Not only is McCarthy presiding over a razor-thin majority, but he agreed to concessions that give the most extreme corner of the GOP considerable influence.

Still, Goldman Sachs is expecting a deal on the debt ceiling will be reached, eventually.

“We think ultimately a solution will be found,” Hatzius said. “These solutions are often found at the very last moment.”

Assuming the United States gets through the debt ceiling episode, Goldman Sachs is optimistic about the prospects for the US economy.

“We don’t expect a recession,” Hatzius said, noting his firm sees a still-significant 35% chance of a recession, compared with the consensus on Wall Street of roughly 65%. “Our baseline is a soft-landing.”

And yet a wave of major companies have announced layoffs in recent weeks, including tech giants such as Microsoft and Amazon as well as financial firms like BlackRock and Goldman Sachs itself.

Goldman Sachs expects the red-hot labor market will continue to cool down, but only gradually. Hatzius does not see the economy losing jobs on a monthly basis at all this year, though he said monthly payroll growth could slip below 100,000.

That deceleration, combined with the housing slowdown, unwinding of supply chain turmoil and impact from the war in Ukraine should help bring down inflation without causing a downturn.

Hatzius expects inflation will go from 9.1% last summer to the 2% to 3% range by late this year or 2024.

“I think inflation has pretty clearly peaked,” Hatzius said, adding that he has “relatively high confidence” on that call.

The Goldman Sachs economist said his forecast is for the US economic expansion to continue through the 2024 presidential election, though that’s not a slam-dunk.

“The further out you go in time…the bigger the risk that something bad hits you along the way and you do get a recession,” Hatzius said. “By the time you get to November 2024, it becomes a closer call.”

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NYC bike path terror attack: Jury to start deliberating in trial for Sayfullo Saipov

Closing arguments wrapped Tuesday in the trial for New York City bike path terror attack suspect Sayfullo Saipov, accused of murdering eight people and injuring many more.

The jury was set to begin deliberating on Wednesday, CBS News reported.

In the three-hour closing argument Tuesday, prosecution said Saipov turned the “bike path into his battlefield” on behalf of ISIS, according to the outlet.

Assistant U.S. Attorney Jason Richman said Saipov was smiling when he asked to hang the flag of the Islamic State group in his Manhattan hospital room after the Oct. 31, 2017, attack he carried out with a speeding rental truck. Prosecutors say it was the worst terrorist attack to strike New York since 9/11.

DRAMATIC NEW VIDEO SHOWS MOMENTS BEFORE NYC TRUCK ATTACK DRIVER SAYFULLO SAIPOV IS SHOT BY POLICE

Saipov, 34, steered the truck onto a bike path along the Hudson River and the West Side Highway that is popular with tourists and Manhattan residents, mowing down bike riders.

Federal prosecutors are seeking the death penalty.

Sayfullo Saipov

Sayfullo Saipov
(St. Charles County, Mo., Department of Corrections / KMOV via AP / File)

Earlier in the trial, the jury was played shocking video that showed the rental truck barreling toward the bike path at high speed, striking a yellow school bus filled with children.

Richman urged jurors to convict Saipov of all charges in a case that could result in the death penalty. If the jury returns a guilty verdict on all charges after starting deliberations, a penalty phase of the trial will begin a week later. Unless jurors unanimously choose death, the sentence would be life in prison.

Individuals who were injured or lost loved ones at the hands of the Uzbek man were among those who testified during the trial.

A law enforcement officer walks by a crime scene, Nov. 1, 2017, after a driver mowed down people on a riverfront bike path near the World Trade Center in New York.

A law enforcement officer walks by a crime scene, Nov. 1, 2017, after a driver mowed down people on a riverfront bike path near the World Trade Center in New York.
(AP Photo / Mark Lennihan / File)

“He targeted his victims without mercy,” Richman said. That night, the prosecutor added, “he smiled. He was proud. He was happy with what he had done that day. He was happy about the terrorist attack. … He had done what he came to do.”

Richman said Saipov only stopped his motorized rampage when he struck a small school bus, injuring children. Otherwise, he said, Saipov planned to head to the Brooklyn Bridge and kill as many people as he could there. He was arrested after he pointed black pellet and paintball guns at a police officer, who shot him.

In this courtroom sketch, Assistant U.S. Attorney Jason Richmond gives the government summations in Manhattan federal court on Tuesday, Jan. 24, 2023, in New York, holding up a knife that defendant Sayfullo Saipov allegedly possessed during his attack.

In this courtroom sketch, Assistant U.S. Attorney Jason Richmond gives the government summations in Manhattan federal court on Tuesday, Jan. 24, 2023, in New York, holding up a knife that defendant Sayfullo Saipov allegedly possessed during his attack.
(Elizabeth Williams via AP)

During the trial, defense lawyers haven’t contested that Saipov carried out the attack.

But they say he should be acquitted of a racketeering charge because prosecutors were wrong to claim that he carried out the attack so that the Islamic State group would let him become a member.

Defense lawyer David Patton said Saipov was expecting to die in the attack.

In this courtroom sketch, defendant Sayfullo Saipov listens during closing statements in Manhattan federal court, Tuesday, Jan. 24, 2023, in New York.

In this courtroom sketch, defendant Sayfullo Saipov listens during closing statements in Manhattan federal court, Tuesday, Jan. 24, 2023, in New York.
(Elizabeth Williams via AP)

“He did not expect to be here before all of you and did not expect to be joining any organization,” Patton said. And that, he added, means Saipov is not guilty of racketeering.

Patton said that to do something “as awful” as what his client did, he had to already consider himself a member of the Islamic State group.

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He said Saipov had an “expectation that he would die by police shooting.”

Saipov, who has been imprisoned without bail since the attack, legally moved to the U.S. from Uzbekistan in 2010. He lived in Ohio and Florida before joining his family in Paterson, New Jersey.

Fox News’ Maria Paronich and the Associated Press contributed to this report.

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Michael Bloomberg Fast Facts



CNN
 — 

Here is a look at the life of Michael Bloomberg, former New York mayor and 2020 Democratic presidential candidate.

Birth date: February 14, 1942

Birth place: Boston, Massachusetts

Birth name: Michael Rubens Bloomberg

Father: William Henry Bloomberg, bookkeeper

Mother: Charlotte (Rubens) Bloomberg, office manager

Marriage: Susan Brown (1976-1993, divorced)

Children: Georgina, 1983; Emma, 1979

Education: Johns Hopkins University, B.S. in electrical engineering, 1964; Harvard Business School, M.B.A., 1966

Religion: Jewish

One of four New York City mayors to serve three terms.

Left the Democratic party in 2001 and won his first two mayoral terms as a Republican. His third mayoral term was won as an independent, and then he rejoined the Democratic party in 2018.

Diana Taylor has been his companion for more than 20 years.

As mayor of New York, Bloomberg made sweeping changes to city schools, transportation, including extending subway lines, and public health, implementing extensive regulations targeting smoking and obesity.

Since 2006, Bloomberg Philanthropies, an umbrella organization of Bloomberg’s charities which includes the nonprofit Bloomberg Family Foundation, has donated billions to political interests and causes such as education, the environment and public health.

1966-1981 – Works as a clerk, and later partner at Salomon Brothers in New York.

1981 – Co-founds Bloomberg L.P. (formerly Innovative Market Systems) using a $10 million partnership buyout from Salomon Brothers.

1982 – Creates the Bloomberg terminal, a software system with a specialized keyboard used by financial professionals to trade stocks electronically and access live market data.

1990 – Co-founds Bloomberg News (formerly Bloomberg Business News).

1994 – Launches Bloomberg Television (formerly Bloomberg Information TV).

1996-2002 – Serves as chairman of the Johns Hopkins University’s board of trustees.

1997 – His memoir, “Bloomberg by Bloomberg,” is published.

November 6, 2001 – Is elected mayor of New York.

November 8, 2005 – Is elected to a second term.

November 3, 2009 – Is elected to a third term after spending more than $100 million on his reelection campaign. In October, the New York City Council voted to extend the city’s mayoral term limits from two four-year terms to three.

May 2012 – Announces a proposal to ban the sale of sugary drinks larger than 16 ounces at restaurants, food carts and any other establishments that receive letter grades for food service. On June 26, 2014, New York’s Court of Appeals rules that New York City’s ban on large sugary drinks, which was previously blocked by lower courts, is illegal.

July 27, 2016 – Endorses Hillary Clinton for president at the Democratic National Convention in Philadelphia.

November 24, 2019 - Announces his late-entry Democratic presidential bid, unveiling a campaign squarely aimed at defeating President Donald Trump.

November 24, 2019 – Bloomberg News Editor-in-Chief John Micklethwait releases a statement addressing how the network will cover the 2020 presidential campaign and reveals that it will not investigate Bloomberg or any other Democratic candidates.

February 10, 2020 – Audio is posted online of Bloomberg from 2015, defending his use of “stop and frisk” as mayor by describing the policy as a way to reduce violence by throwing minority kids “up against the walls and frisk[ing] them.” Bloomberg later says his 2015 comments about the controversial stop and frisk policing policy do not reflect the way he thinks or the way he led as mayor of New York City.

February 18, 2020 – Qualifies for his first Democratic presidential debate, by polling four times at or above 10% nationally.

February 18, 2020 – A campaign adviser tells CNN that Bloomberg would sell his financial information and media company if he’s elected president, in an effort to be “180 degrees away from where Donald Trump is on these issues.”

February 19, 2020 – Faces criticism in first presidential debate from other Democratic candidates regarding campaign spending, his record on policing tactics as mayor of New York and misogynistic comments he allegedly made about women at his company in the 1980s and 1990s.

March 4, 2020 – Ends his presidential campaign and endorses Joe Biden.

September 3, 2020 – Bloomberg’s charity, Bloomberg Philanthropies, announces he is donating $100 million to the nation’s four historically Black medical schools to help ease the student debt burden for the next generation of Black physicians.

September 25, 2020 – Bloomberg announces $40 million in TV ads supporting Biden statewide in Florida.

February 2, 2022 – Joseph Beecher is arrested, accused of breaking into the Colorado ranch owned by Bloomberg and kidnapping a Bloomberg employee. Beecher demanded to know the location of Bloomberg’s daughters, according to an arrest warrant affidavit. Beecher is awaiting a February 8 federal court hearing in Wyoming, where he was found with the employee, who was unhurt.

February 9, 2022 – Bloomberg is nominated to serve as the chair of the Defense Innovation Board.

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Living a ‘good life’ requires some hard questions

A willingness to ask tough questions about what defines a life well-lived is the key to well-being, argues Bernard Reginster.

Every January, millions of people set new goals in hopes of improving their lives. Driven to boost their health and happiness, they scour books and news articles full of meditation tips, exercise routines, and diet ideas.

For those who make New Year’s resolutions, doctors and psychologists have become the ultimate experts. But whither the philosopher—that rare breed of person who spends all day, every day, contemplating the meaning of life?

Reginster, a professor of philosophy at Brown University, believes in asking the hard questions: What is the mark of a life well-lived? What is the difference between a happy life and a good life? He argues that if people can’t answer these questions for themselves, they’re unlikely to find satisfaction in any of those scientist-approved New Year’s resolutions.

After all, how can someone find happiness in any new habit if they haven’t yet defined what “happiness” actually means to them?

“If you believe that what makes your life good is to experience as much pleasure as possible, and you want to know how to maximize pleasure, there’s no question that you will want to turn to research by empirical psychologists,” Reginster says.

“But that question comes downstream from the fundamental questions of whether a pleasant life is a good life, and what ‘good’ even means—and those are questions for philosophers,” he says.

Here, Reginster answers questions about his own background studying the philosophy of well-being, why psychological studies can miss the mark in identifying the key to happiness, and how philosophy could help people discover what’s most important in life:

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Brad Pitt and George Clooney step out in New York City, reunite for new movie

The boys are back in town. 

Hollywood stars Brad Pitt and George Clooney were spotted out in New York City on Tuesday filming their upcoming movie “Wolves.”

Pitt, 59, and Clooney, 61, were having a twinning moment as the two actors both sported leather jackets and gray pants with black shoes. 

BRAD PITT’S WILD YEAR: FROM LAWSUITS TO ABUSE ALLEGATIONS AND A NEW RELATIONSHIP

Despite the cold, winter weather, the “Ocean’s Eleven” stars appeared to be having a great time, as they were spotted at a Drive-In Hotel in Harlem. 

Pitt, 59, and Clooney, 61, were having a twinning moment, both sporting leather jackets and gray pants with black shoes.

Pitt, 59, and Clooney, 61, were having a twinning moment, both sporting leather jackets and gray pants with black shoes.
(Getty Images)

Pitt and Clooney were additionally seen laughing together as they sat in a dark blue vehicle on the set. 

Clooney flashed his pearly whites behind the wheel, while Pitt smiled from the passenger seat. 

Pitt and Clooney were additionally seen laughing together as they sat in a dark blue vehicle on the set. 

Pitt and Clooney were additionally seen laughing together as they sat in a dark blue vehicle on the set. 
(Getty Images)

In another photo, Pitt was seen in a teal velour jumpsuit. He wore a white shirt underneath with white sneakers and carried a yellow scarf with a red bag over his shoulder.

Brad Pitt was also seen in a teal velour jumpsuit. He wore a white shirt underneath with white sneakers and carried a yellow scarf with a red bag over his shoulder.

Brad Pitt was also seen in a teal velour jumpsuit. He wore a white shirt underneath with white sneakers and carried a yellow scarf with a red bag over his shoulder.
(Getty Images)

The Apple TV+ thriller “Wolves” is about “two lone fixers who are assigned the same job,” according to the streaming company. The film is written and directed by John Watts.

Despite the cold, winter weather, the "Ocean’s Eleven" stars appeared to be enjoying themselves on set.

Despite the cold, winter weather, the “Ocean’s Eleven” stars appeared to be enjoying themselves on set.
(Getty Images)

GEORGE CLOONEY SAYS TWINS ‘DON’T REALLY CARE’ HE’S A STAR AT KENNEDY CENTER HONORS WITH WIFE AMAL CLOONEY

This isn’t the award-winning actors’ first time working alongside one another. They previously starred in the “Ocean’s” franchise and “Burn After Reading” together.

In 2022, both Pitt and Clooney were busy working on several films. 

Pitt starred in the drama-comedy “Babylon,” which was released in theaters last December. He was also in the assassin comedy “Bullet Train” and was featured in Sandra Bullock’s “The Lost City.”

Matt Damon, Brad Pitt, George Clooney and Andy Garcia attend the London premiere of "Ocean's Eleven" in 2001.

Matt Damon, Brad Pitt, George Clooney and Andy Garcia attend the London premiere of “Ocean’s Eleven” in 2001.
(Dave Hogan/Mission/Getty Images)

Meanwhile, Clooney recently worked with Julia Roberts on “Ticket to Paradise.” The coveted actor was also recognized at the Kennedy Center Honors in Washington, D.C., last month.

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Clooney was one of five artists celebrated, including Amy Grant, Gladys Knight, Tania León, and members of the band U2: Bono, The Edge, Adam Clayton and Larry Mullen Jr.

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His co-star Roberts showed support for her celebrity friend by wearing a black gown covered with framed photos of Clooney to the event.

“It’s cool to be out here with my friends, and you don’t have to sit and wonder if you’re going to win either, you already know… which is helpful,” Clooney told Fox News Digital.

Julia Roberts wore a dress covered in photos of her friend George Clooney at the 45th annual Kennedy Center Honors.

Julia Roberts wore a dress covered in photos of her friend George Clooney at the 45th annual Kennedy Center Honors.
(Gail Schulman/CBS via Getty Images)

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Updated boosters are cutting the risk of getting sick from Covid-19 by about half



CNN
 — 

The updated Covid-19 boosters are cutting the risk that a person will get sick from the coronavirus by about half, even against infections caused by the rapidly spreading XBB.1.5 subvariant.

New studies, conducted by researchers at the US Centers for Disease Control and Prevention, are among the first looks at how the bivalent boosters have continued to work in the real world as the virus has evolved. The data shows that the boosters are continuing to offer substantial protection against currently circulating variants.

The near-real-time data was collected by the federally funded Increased Community Access To Testing program, which administers Covid-19 tests through pharmacies. It includes results for adults receiving tests at participating pharmacies from December 1 to January 13.

Of nearly 30,000 test results included in the analysis, more than 13,000 (47%), were positive for Covid-19.

More people who tested negative had gotten an updated bivalent booster compared with those who tested positive.

On average, people in the study who had not gotten a bivalent booster also had not had a dose of a Covid-19 vaccine in more than a year. That’s about the same as the national average, the study authors said. Their protection against illness was probably very minimal, they said.

The study results show that the updated boosters are most effective for younger adults.

For adults between the ages of 18 and 49, the boosters cut the odds of getting a symptomatic infection caused by the BA.5 subvariant by 52%, and it cut the odds of getting an infection caused by XBB or XBB.1.5 by 49%. For adults 50 to 64, the new boosters cut the odds of getting sick with Covid-19 by 43% for BA.5 and 40% for XBB subvariants. For those 65 and older, the boosters cut the odds of an infection with symptoms by 37% and 43% for the BA.5 and XBB subvariants, respectively.

Ruth Link-Gelles, a senior epidemiologist at the CDC and lead study author, said at a news briefing Wednesday that these vaccine effectiveness numbers are averages. Because everyone is unique in terms of their underlying health, their past exposure to the virus and other factors, these estimates of vaccine effectiveness may not apply on an individual level. She said it’s important to think of them on population level.

For people who are wondering whether the protection from the bivalent booster they got in September has worn off by now, it’s too early to know how waning would work with these new two-strain shots, Link-Gelles said.

So far, there’s little evidence of waning effectiveness two to three months after people got their shots.

“It’s too early, I think, to know how waning will happen with the bivalent vaccine. We know from the older vaccines that we do see protection decrease over time, especially against symptomatic infection. Just like with overall protection, what we’ve seen in the past is, your protection lasts longer for more severe illness,” Link-Gelles said.

Researchers don’t have data past three months, she said, but based on experience, she would expect protection against severe disease and death to be higher and last longer than these results against infections.

“We will continue to monitor it over time in the coming months,” she said.

The study authors said that these are just estimates of how well the vaccines are protecting people against an infection that brings on symptoms like cough or fever. They are probably working even better against more severe outcomes like hospitalization and death.

“What we know from past experience is generally that the vaccines protect better against more severe disease. So these are estimates for symptomatic infection and we would expect that similar estimates for hospitalization and death would be higher,” Link-Gelles said.

Asked how well the two-strain vaccines may be working compared with the older one-strain shots, Link-Gelles said it was impossible to know.

“We can’t in the US do a direct, head-to-head comparison of the monovalent and the bivalent vaccines because they were never authorized at the same time,” she said. Because protection wanes over time, you’d need to compare groups of people who got each kind of shot at the same time.

“What this tells us is that people that had the bivalent vaccine were better protected than people that were up to date previously, had all their monovalent doses and had not gotten the bivalent vaccine,” Link-Gelles said.

The CDC said it was able analyze the data and publish it so quickly thanks to the use of a shortcut. Rather than sequencing the genomes of each positive result, the researchers relied on a different marker to distinguish between variants.

The tests used in the study rely on a series of probes, or markers, to identify a positive case. Some variants of the virus that causes Covid-19 have mutations in their spike protein that causes one of the test markers to fail. This is called an S-gene target failure.

In the study, test results that showed an S-gene target failure were considered to be an infection caused by a BA.5 subvariant. Those that were S-gene target positive were considered to be caused by the XBB or XBB.1.5 sublineage.

As the study continued, XBB.1.5 became a bigger player in the variant mix.

“Later in the study period, most would be XBB.1.5,” said Heather Scobie, an epidemiologist at the CDC.

This gave the researchers confidence that the vaccine effectiveness results reflect how well the vaccines are working right now.

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Method helps finds source of epilepsy seizures before they begin

A measure of brain activity known as causal flow can help locate the source of epilepsy seizures before they occur, according to a new study.

The finding could reduce the need for invasive procedures in treating drug-resistant forms of the disorder.

According to the World Health Organization, about 50 million people worldwide live with epilepsy. The neurological disorder is marked by recurrent seizures—sudden bouts of abnormal electrical activity in the brain.

“Seizures are often described as electrical storms in the brain,” says coauthor Mukesh Dhamala, an associate professor in Georgia State University’s Neuroscience Institute and physics and astronomy department. “And that can take over normal functioning. Patients can lose consciousness and control of their behaviors for seconds to minutes.”

While some cases of epilepsy can be treated with medication, about 30% are considered drug-resistant. These cases require surgical intervention on the brain area where the seizure starts, known as the seizure focus.

Neurosurgeons look for areas of abnormal activity using intracranial electroencephalogram (iEEG), a procedure in which electrodes are surgically implanted into the brain for the duration of the test. To work, the patient must have a seizure while the iEEG is recording.

This approach to locating the seizure focus is successful only 40 to 60% of the time for multiple reasons. First, the patient must have a seizure while the iEEG is recording. When seizures occur sporadically and without warning, this can be a problem. Second, the iEEG can miss a focus region or detect multiple regions of abnormal activity. In these cases, it can be difficult—if not impossible—to visually interpret the iEEG recordings.

“That’s where we come in—to help neurosurgeons by analyzing recorded data,” Dhamala says.

Rather than looking at the output from each individual electrode, Dhamala and his team have started to combine data from each point to get a broader picture of the brain’s activity. Like using seismographs to determine the location and strength of an earthquake, these data points can be used to determine causal flow, a measurement that quantifies the activity of this broader network.

Previously, Dhamala and his colleagues used high-frequency activity known to be present during seizures to show that causal flow can locate foci. In its recent study, the team was able to do the same using low-frequency activity, which occurs before a seizure starts. Their findings suggest that using low frequencies to determine causal flow could help locate a seizure long before one occurs.

“The method can potentially open up a whole new possibility of localizing seizures with a… non-invasive approach,” Dhamala says. “That’s the idea.”

In the future, neurosurgeons may be able to locate foci without waiting for patients to have more seizures and do so even with less invasive techniques. The team is now conducting research on the use of functional magnetic resonance imaging, which measures low-frequency activity, as an alternative.

Sushma Ghimire, a recent graduate of the Georgia State doctoral program in physics, and Charles Epstein, a neurophysiologist and professor at Emory University are coauthors of the study, published in the Journal of Clinical Neurophysiology.

Source: Georgia State University

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