Does having a teen feel like living with a chimpanzee? You may not be far off, study shows

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Chimpanzee teens may not be so different from the ones living in our homes, a new study says.

Except that your teen might be more impulsive.

Researchers worked with 40 chimpanzees born in the wild while they were at a sanctuary in the Republic of Congo, playing games that tested the adolescent animals’ orientation toward risk-taking and impulsivity, according to the study published January 23 in the Journal of Experimental Psychology: General by the American Psychological Association.

“Human adolescents are grappling with changing bodies and brains, and tend to be more impulsive, risk-seeking, and less able to regulate emotions than adults,” said lead study author Dr. Alexandra Rosati, associate professor of psychology and anthropology at the University of Michigan, via email. “Chimpanzees face many of the same kinds of challenges as humans as they grow up.”

The study described chimpanzees’ adolescence as a period from about ages 8 to 15 in a 50-year life span. Like young humans, they experience rapid hormone changes, new social bonds, increased aggression and a competition for social status.

Teen chimpanzees are overlooked in studies compared with infants and adults, said Dr. Aaron Sandel, an assistant professor of anthropology at the University of Texas at Austin, who was not involved in the current study.

“For a while there was a pretty big gap in the literature on (chimpanzee) adolescents,” Sandel said, noting that researchers often don’t focus on this period. Scientists may avoid studying teen chimps because their own human experiences with teenage years are complicated, he said.

The new study found that adolescent chimpanzees were more likely to take risks in their games than their adult counterparts, but they just as likely would wait for a greater delayed reward.

But human teens are known to be more likely to take a smaller, more immediate reward, the study noted.

The chimpanzees underwent two tests with food rewards. These animals tended to dislike cucumbers while liking peanuts somewhat and loving bananas.

The first test involved a bit of a gamble. Both adult and teen chimpanzees were asked to choose between two containers: one that always had peanuts and another that had either the dreaded cucumber or treasured banana, the study said.

The adolescent chimps were more likely to take a risk and go for the cucumber or banana container than the adults, the study said. Both groups showed similar negative reactions – such as moaning, whimpering, screaming and banging on the table – when they ended up with a cucumber.

The second test resembled a well-known one that has been given to human children. Chimpanzees had the option of having one banana slice immediately or waiting for a minute and then getting three slices.

Both adults and adolescents waited for the three slices at a similar rate, but the teens were more likely to throw a fit while they waited a minute, the study said.

In a similar test, human teens were more likely to take the smaller treat right away, according to the study.

“Prior work indicates that chimpanzees are quite patient compared to other animals, and this study shows that their ability to delay gratification is already mature at a fairly young age, unlike in humans,” Rosati said.

Sandel noted that it is important to be careful about comparing the experience of humans with other animals. While primates are our closest relatives, we are different species, he pointed out.

So how might a parent handle a teen who engages in risky behavior and hates to wait for a reward?

The first step is to understand what is going on in their developing brains, said Dr. Hina Talib, an adolescent medicine specialist and associate professor of pediatrics at the Albert Einstein College of Medicine in New York City.

“I think teenagers get a bad rap,” she said. “We often think of them as risky little devils. It does come from some element of truth.”

The human teenage years are a time of explosive growth and development, she added.

Their brains are wired to seek out new experiences and information, which often means taking risks, Talib said.

At this time, they can try new things, build their ideas of who they are and try on different identities, said Tina Bryson, a Pasadena, California, therapist and author of “The Power of Showing Up: How Parental Presence Shapes Who Our Kids Become and How Their Brains Get Wired.”

They learn from the information they gain, which can help them manage their behavior better – eventually, Talib said.

Families can encourage them to try new things, she said, while providing ground rules and support that will help keep them safe.

“We want you to go anywhere and do everything … Here is where we might step in or where we have house rules about something,’” Talib recommended that parents say. Your conversations should be “coming from a perspective of we are here as the floor, as the safety net as you go and have these amazing trapeze experiences.”

And while their brains are growing a lot, not every area is able to be fully and optimally utilized at the same time.

Late middle and early high schoolers might be relying on the parts of the brain that rule emotion and reactivity, she added, while their decision-making and reasoning parts are busy growing.

That doesn’t mean that teens are not capable of good decision-making and long-term planning, she added – you just have to help set them up for success.

“When things are calm, they are able to problem solve just as well as adults,” Talib said. Help them stay calm when they are in trouble and need to solve a problem and save the difficult conversations for when they are no longer stressed out, she added.

Instead of worrying about how to get rid of their impulsivity, Bryson recommended finding ways to help strengthen empathetic, thoughtful, and reasoned decision-making.

Encourage them to pause before acting and walk through the thinking process with them, she said. You can also talk through how you think through your own decisions, Bryson said.

And while their brains may be undergoing changes, be sure to call out the things they are doing well, Talib said.

“The more you do that, the more you help them see themselves in a positive light, the more that gets hardwired in them,” she said, “and they are better able to face the world around them.”

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Mystery solved: Why switchgrass takes the summer off

Researchers have solved a puzzle that could help switchgrass realize its full potential as a low-cost, sustainable biofuel crop and curb our dependence on fossil fuels.

Among switchgrass’s attractive features are that it’s perennial, low maintenance, and native to many states in the eastern US. But it also has a peculiar behavior working against it that has stymied researchers—at least until now.

Berkley Walker’s team in the plant biology department at Michigan State University has revealed why switchgrass stops performing photosynthesis in the middle of the summer—its growing season—limiting how much biofuel it yields.

Published in Frontiers in Plant Science, the knowledge is a key piece to overcoming this quirk and getting the most out of switchgrass.

“We want bigger plants, period, so being able to crack this and lift this limitation, that is the goal,” says Mauricio Tejera-Nieves, a postdoctoral researcher and the study’s lead author.

Tejera-Nieves, Walker, and colleagues discovered the explanation for this limitation in switchgrass’s rhizomes. These are little knobby structures that live underground among the plant’s roots.

If you’ve ever sliced or shredded ginger, you’ve held a rhizome. Rhizomes store food in the form of starch to help plants survive winter, and that starch is made from the sugars photosynthesis produces. Once switchgrass rhizomes are full of starch, they signal the plant to stop making sugars and adding biomass through photosynthesis.

Switchgrass ‘banking’

Tejera-Nieves compared the rhizomes to a bank, albeit a slightly unusual one.

“Imagine getting a call from your bank and they tell you, ‘Hey, your account is full. You can take a vacation, go on sabbatical, do whatever you want. Just stop working because we’re not storing any more money,’” Tejera-Nieves says.

“It’s a very conservative strategy, but it’s one that works for switchgrass. The longer it’s doing photosynthesis in nature, the more likely it is that an animal will eat it or something else bad will happen.”

Although this evolutionary strategy has worked to the plant’s advantage in nature, it is a disadvantage for humans who want to ferment switchgrass’s biomass into biofuel. By understanding the root cause of this behavior, though, researchers can start looking for ways around it.

“Now we can start looking for breeding solutions,” says Walker, an assistant professor in the College of Natural Science who also works in the department of energy’s Plant Research Laboratory. “We can start looking for plants that have an insatiable appetite for photosynthesis.”

Why take summers off?

Switchgrass has yet to join plants including corn and sugarcane as a commercialized source of biofuel.

But that makes sense because those established crops have a huge head start, the researchers say.

Farmers have selected and reproduced versions of those crops that have qualities that are attractive to us, such as higher sugar content, for thousands of years.

Humanity’s interest in switchgrass as a biofuel source is much more recent in comparison. So, it’s only natural that switchgrass exhibits some suboptimal behaviors that researchers would like to iron out, like stopping photosynthesis without explanation.

“The plants get to about midseason and say, ‘Okay, we’re done,’” says Walker.

“As a researcher, you’re literally asking, ‘Why are you doing that? It’s warm, the sun is out, and your leaves are green. What is happening?’” says Tejera-Nieves.

Tejera-Nieves joined Walker’s team with a hypothesis to answer that as well as the means to test it with support from the Great Lakes Bioenergy Research Center, or GLBRC. He suspected that a lack of water might be playing a role.

In addition to awarding Tejera-Nieves a fellowship, the GLBRC built what are called rainfall exclusion shelters in the fields at Michigan State’s W.K. Kellogg Biological Station. These do exactly what their name promises: They exclude rain. Plants underneath the shelters stay dry while their neighbors outside can freely soak up sprinkles, showers, and storms.

The shelters presented the perfect place to test Tejera-Nieves’ idea, even if it didn’t go exactly as he initially predicted.

“If water limitation was the reason for the behavior, the plants under the shelters would do poorly,” Tejera-Nieves says. “But they didn’t. After six months of water limitation, the plants under the shelter were just as happy as the plants outside.”

So, he needed to dig a little deeper—literally—to look at what was happening in the rhizomes. He found that the starch levels of all the plants grew over time until they hit a peak level and then would remain flat. Once that happened, photosynthesis in the plants’ leaves switched off.

“Once the rhizomes are full, the plant just stops,” Tejera-Nieves says.

“You can see it so clearly in the data,” Walker says. “The plants do photosynthesis in the summer to save carbon for the winter and, as soon as they’ve got enough, they shut down.”

One of the next steps for the team is developing a better understanding of the molecular machinery that coordinates this photosynthesis shutdown. That knowledge could reveal even more clues about how to override the plant’s behavior and may prove handy for biofuel crops beyond switchgrass.

“You see similar trends with photosynthesis across perennials,” Walker says. “We’d have to look to be sure, but we think it could be the same mechanism.”

The US Department of Energy, Office of Science, Office of Biological and Environmental Research, the Great Lakes Bioenergy Research Center, the National Science Foundation Long-term Ecological Research Program at Kellogg Biological Station, and Michigan State University AgBioResearch funded the work.

Source: Matt Davenport for Michigan State University

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Bystander wounded in Arizona RV park police shootout

A bystander was struck by gunfire during a shootout between a suspect and officers at a recreational vehicle park in northwestern Arizona, authorities said.

Bullhead City police said officers went to the Silver View RV Resort on Friday to investigate reports of a man in a bulletproof vest pointing a gun at people.

From inside a trailer, the suspect shot at officers, who returned fire, police said in a statement. One of the rounds from the suspect ripped through another trailer “and struck an innocent bystander.”

The victim was taken about 95 miles north to a Las Vegas hospital and was expected to survive. No officers were hurt.

ARIZONA’S CRIME CONCERNS COULD JEOPARDIZE LITTLE ROCK MAYOR’S REELECTION
 

A man who was waving a gun at people in a bulletproof vest at an Arizona RV park was taken into custody after eight hours of locking himself in a trailer. An innocent bystander was struck during the shootout and was treated at the hospital. 

A man who was waving a gun at people in a bulletproof vest at an Arizona RV park was taken into custody after eight hours of locking himself in a trailer. An innocent bystander was struck during the shootout and was treated at the hospital. 

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Police identified the suspect Saturday as Bullhead City resident Kyle Schafer, 41, but did not say what charges he may face.

Schafer locked himself inside his trailer for nearly eight hours before surrendering and being taken into custody, police said. He was also brought to a Las Vegas hospital, with unspecified injuries.

Bullhead City is located on the Arizona side of the Colorado River, near the juncture with Nevada and California. It is home to about 41,000 people.

An outside agency, Lake Havasu City Police, will investigate the shooting for Bullhead City police in line with the department’s protocol for cases where officers fire their weapons.

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3 out of 4 parents agree social media distracts students

The vast majority of parents believe social media is a major distraction for students, according to a new nationwide study.

For the online study, conducted in November and December, researchers surveyed a nationally representative sample of more than 10,000 parents of K-12 students. An overwhelming majority from across racial groups—African American (70%), Asian (72%), white (75%), Hispanic/Latino (70%)—agreed that social media is a distraction.

Parents of children who attend private schools (82%) were more likely to see social media as a distraction than parents of children in public schools (73%) or charter schools (73%) or those being homeschooled (67%). Interestingly, parents with children in high school (74%), middle school (73%), and elementary school (73%) were equally concerned about the issue.

“Suing social media companies or banning cellphones in classrooms may be trendy, but is unlikely to help students.”

School leaders are also worried. In early January, Seattle Public Schools sued the tech giants behind TikTok, Instagram, Facebook, YouTube, and Snapchat, claiming they’ve created a youth mental health crisis. Most schools prohibit cellphone use in the classroom.

“Suing social media companies or banning cellphones in classrooms may be trendy, but is unlikely to help students,” says Vikas Mittal, a professor of marketing at Rice University’s Jones Graduate School of Business, who conducted the 2022 Collaborative for Customer-Based Execution and Strategy (C-CUBES) K12 Parent Voice Study.

Cellphone usage and social media browsing is ingrained among school-age children, he argues. A Pew Research Center study of teens found more than 95% have access to a cellphone, 94% use the internet almost constantly or several times a day, and 54% say it would be hard for them to give up social media.

“Many years ago, schools were in a race to provide every student with internet access,” Mittal says. “It was seen as a panacea for improving academic achievement. That policy seems to have had some unintended consequences.

“The distractive effect of social media is only exacerbated due to widespread internet access, and today’s school leaders must thread a difficult needle,” he continues. “They must continue providing students with high-quality and equitable internet access due to its potential educational benefits.”

“Policies like curtailing cellphone usage in classes to ensure teachers can teach effectively are necessary but quite limiting,” he adds. “School leaders must proactively work with parents to educate children about the potential downside of social media usage and teach them strategies to self-manage potentially addictive behaviors associated with social media.”

Source: Rice University

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WHO seeks to expand role in tackling next global health emergency, but faces funding issues

The World Health Organization will push at its board meeting this week for an expanded role in tackling the next global health emergency after COVID-19, but is still seeking answers on how to fund it, according to health policy experts.

The Geneva meeting sets the programme for the U.N. agency this year – as well as its future budget – with the WHO facing two key challenges: a world that expects ever more from its leading health body, but which has not yet proven willing to fund it to tackle those challenges.

At the Executive Board’s annual meeting from Jan. 30-Feb. 7, countries will give feedback on WHO Director-General Tedros Adhanom Ghebreyesus’ global strategy to strengthen readiness for the next pandemic which includes a binding treaty currently being negotiated.

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“I think the focus is very much on the programme budget, then sustainable financing,” Timothy Armstrong, WHO director for governing bodies, told journalists when asked about the agenda.

Also on his list was “the position of the World Health Organization, recognizing there is a need for a reinforced central role for WHO” in the global health emergency system.

The WHO is seeking a record $6.86 billion for the 2024-2025 budget, saying that approving this sum would be “a historic move towards a more empowered and independent WHO”.

A woman receives a booster dose of Pfizer-BioNTech vaccine in Bangkok, Thailand, on Jan. 5, 2023.

A woman receives a booster dose of Pfizer-BioNTech vaccine in Bangkok, Thailand, on Jan. 5, 2023.
(REUTERS/Athit Perawongmetha)

But approval will require member states to make good on promises made last year to hike mandatory fees – a fact which is uncertain since the deal was always subject to conditions.

“What we are currently seeing is that some member states are now trying to pre-condition lots of things,” said a source close to the talks, saying it “remains to be seen” if all countries will commit to raising fees. Reuters could not immediately establish which countries might withhold support.

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The current base budget, which does not include the funding changes, has a nearly $1 billion financing hole, a WHO document showed – although that gap is not unusual at this point, two sources added. However, one did add that it was “absurd” that the WHO still has to scrabble for money after COVID-19.

“It’s a huge knot,” said Nicoletta Dentico, the co-chair of the civil society platform the Geneval Global Health Hub. “The weakness of WHO is under our eyes.”

The agency is also considering starting big replenishment rounds every few years to top up its coffers, a document showed.

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Pandemic Preparation

The WHO, which celebrates its 75-year anniversary having been set up in 1948, will also use the meeting to advocate for a boosted role in pandemic preparedness, documents showed.

Tedros will call for a Global Health Emergency Council to be set up linked to WHO governance. However, external experts have said such a council needs higher-level political leadership.

“Given that pandemic threats involve and impact almost every sector, it must be an outcome of a UN General Assembly resolution, be appointed by and accountable to it,” Helen Clark, former prime minister of New Zealand and head of the independent panel set up to review the handling of COVID, told Reuters.

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Biden and his team ramp up travel to highlight effects of infrastructure law ahead of State of the Union



CNN
 — 

President Joe Biden and senior administration officials are embarking on a travel swing this week, showcasing what they see as successful measures to rebuild America’s ailing infrastructure.

In what’s been described as a preview of some of the messaging for next week’s State of the Union address, Biden, Vice President Kamala Harris and Cabinet secretaries are all hitting the road to highlight the implementation of the landmark legislation signed into law during the president’s first two years in office. Among those accomplishments are the American Rescue Plan, the Bipartisan Infrastructure Law, the Chips and Science Act, and the Inflation Reduction Act.

The president traveled to Baltimore on Monday to showcase the implementation of his policies, and later this week, he’ll head to New York City and Philadelphia for similar remarks.

The trips are taking place in the lead up to Biden’s State of the Union speech in Washington next week – a national platform where he’s expected to illustrate how his policies are successfully going into effect – and a prospective reelection announcement in the coming months. Biden’s approach is expected to be focused on touting the rebound of the American economy and taking aim at Republican proposals – while still underscoring his desire to work across the aisle.

In Baltimore on Monday, he discussed how the infrastructure law will fund replace the 150-year-old Baltimore and Potomac Tunnel, addressing the largest bottleneck for commuters on the Northeast Corridor between Washington, D C, and New Jersey. The new tunnel will be named in honor of civil rights leader and abolitionist Frederick Douglass.

Speaking from a presidential podium set to the backdrop of an American flag and an Amtrak train on the tracks, Biden recalled that he’d made a thousand trips through the tunnel and walked through it in the 1980s.

“When folks talk about how badly the Baltimore tunnel needs an upgrade, you don’t need me to tell you. I’ve been there and you’ve been there, too,” Biden said.

“You ought to get inside and see,” he remarked, discussing his tour of the tunnel decades ago. “This is a 150-year-old tunnel. I wonder how in the hell it’s still standing.”

“The structure is deteriorating. The roof is leaking. The floor is sinking. This is the United States of America, for God’s sake. We know better than that,” he continued.

When the project is done, Biden said, trains will roll through the tunnel at 110 mph instead of 30 mph, shortening regional MARC train commutes from Baltimore to Washington to 30 minutes.

At Monday’s project kickoff, the president announced an agreement between the state of Maryland and Amtrak, which includes a $450 million commitment for the tunnel replacement project, according to the White House. A project labor agreement between Amtrak and the Baltimore-DC Building and Construction Trades Council was unveiled to cover the first phase of the project. And he also announced an agreement between Amtrak and the North American Builders’ Trade Union “that ensures Amtrak’s large civil engineering construction projects controlled by Amtrak will be performed under union agreements,” according to the White House.

The program is expected to cost approximately $6 billion, of which Bipartisan Infrastructure Law funding could contribute up to $4.7 billion, the White House said. Biden was joined by labor leaders, state and local officials, as well as members of Congress and Transportation Secretary Pete Buttigieg.

On Tuesday, Biden travels to New York City to discuss how Bipartisan Infrastructure Law funding will improve the Hudson River Tunnel, which sees 200,000 passengers passing through each weekday on Amtrak and New Jersey Transit.

On Friday, Biden and Harris are scheduled to travel to Philadelphia to discuss how Bipartisan Infrastructure Law funding is removing lead pipes and ensuring clean water across Philadelphia and the country, the official told CNN.

According to the White House, the pair “will discuss the progress we have made and their work implementing the Biden-Harris economic agenda that continues to deliver results for the American people.”

Housing and Urban Development Secretary Marcia Fudge will also travel to Chicago to discuss progress made to address homelessness as a result of provisions within the American Rescue Plan, according to the official.

While Biden has often embarked on domestic trips to highlight his policies in action, these stops have served as a significant messaging platform since Republicans took control of the House of Representatives this year.

In a speech at a union hall in Virginia, Biden, for example, sought to contrast his economic policies with House Republicans’ effort in the debt limit standoff.

He asked the crowd, “(Why) in God’s name would Americans give up the progress we’ve made for the chaos they’re suggesting?”

“MAGA Republicans,” he added, “are literally choosing to inflict this pain on the American people.”

Despite that heavy emphasis on his warnings about GOP plans, Biden this week is expected to hone in on his ability to work across the aisle to push legislation into law. Specifically, in a preview of the travel, White House press secretary Karine Jean-Pierre underscored Biden’s “success (in) bringing Republicans and independents and Democrats together to pass the Bipartisan Infrastructure Law.”

In Baltimore on Monday, the president brought up his recent trip to Kentucky, where he stood alongside Senate Minority Leader Mitch McConnell to herald the implementation of the massive $1.2 trillion infrastructure bill that McConnell and 18 other Senate Republicans supported.

The policy messaging trips also carry more weight as the prospect of a presidential reelection campaign looms large over the White House.

Biden has been working intensively on his State of the Union Speech speech – including over the weekend – which his team views as a launching pad for the reelection bid. His speeches around the East Coast week will offer a preview of his message as he touts new infrastructure projects.

Behind the scenes, aides are building up a campaign infrastructure and the West Wing is in the process of restructuring for a politically intense two years.

Peppered in between stops to visit projects funded though the proposals which were the bedrock of his 2020 presidential campaign, Biden will participate in events that are part of an intense fundraising push ahead of the campaign announcement.

The travel comes as Biden also contends with a number of simmering issues in Washington – House Republican probes, investigations into classified documents found at his residence and former office and the debt ceiling standoff. The US Treasury is already taking extraordinary measures to keep the government paying its bills after the US hit the debt ceiling set by Congress.

While the president is in Washington on Wednesday in between travel stops, he’s scheduled to meet with House Speaker Kevin McCarthy.

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Can a cough syrup drug help people quit smoking?

Medications like dextromethorphan that are used to treat coughs caused by cold and flu could potentially be repurposed to help people quit smoking cigarettes, a new study shows.

The researchers developed a new machine learning method, where computer programs analyze data sets for patterns and trends, to identify the drugs and say that some of them are already being tested in clinical trials.

Cigarette smoking is risk factor for cardiovascular disease, cancer, and respiratory diseases and accounts for nearly half a million deaths in the United States each year.

While smoking behaviors can be learned and unlearned, genetics also plays a role in a person’s risk for engaging in those behaviors. The researchers found in a prior study that people with certain genes are more likely to become addicted to tobacco.

Using genetic data from more than 1.3 million people, Dajiang Liu, professor of public health sciences, and of biochemistry and molecular biology and Bibo Jiang, assistant professor of public health sciences, both at Penn State, co-led a large multi-institution study that used machine learning to study these large data sets—which include specific data about a person’s genetics and their self-reported smoking behaviors.

The researchers identified more than 400 genes related to smoking behaviors. Since a person can have thousands of genes, they had to determine why some of those genes were connected to smoking behaviors.

Genes that carry instructions for the production of nicotine receptors or are involved in signaling for the hormone dopamine, which make people feel relaxed and happy, had easy-to-understand connections. For the remaining genes, the research team had to determine the role each plays in biological pathways and using that information, figured out what medications are already approved for modifying those existing pathways.

Most of the genetic data in the study is from people with European ancestries, so the machine learning model had to be tailored to not only study that data, but also a smaller data set of around 150,000 people with Asian, African, or American ancestries.

Liu, Jiang, and colleagues identified at least eight medications that could potentially be repurposed for smoking cessation, such as dextromethorphan, which is commonly used to treat coughs caused by cold and flu, and galantamine, which is used to treat Alzheimer’s disease. The study is published in Nature Genetics.

“Repurposing drugs using big biomedical data and machine learning methods can save money, time, and resources,” says Liu, a Penn State Cancer Institute and Penn State Huck Institutes of the Life Sciences researcher. “Some of the drugs we identified are already being tested in clinical trials for their ability to help smokers quit, but there are still other possible candidates that could be explored in future research.”

While the machine learning method was able to incorporate a small set of data from diverse ancestries, Jiang says it’s still important for researchers to build out genetic databases from individuals with diverse ancestries.

“This will only improve the accuracy with which machine learning models can identify individuals at risk for drug misuse and determine potential biological pathways that can be targeted for helpful treatments.”

The authors declare no conflicts of interest. A full list of authors on the project can be found in the manuscript.

The National Institutes of Health and Penn State College of Medicine’s Biomedical Informatics and Artificial Intelligence Program in the Strategic Plan supported the work. The views of the authors do not necessarily represent the views of the funders.

Source: Penn State

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Indonesia local trader forged ingredient label that may have led to cough syrup deaths of 200 kids

Indonesian police said on Monday a local trader of industrial-grade chemicals sold them as pharmaceutical-grade, leading to their use in medicated syrups that authorities suspect may have caused deaths of more than 200 children across the country.

Authorities have said two ingredients, ethylene glycol (EG) and diethyelene glycol (DEG), found in some syrup-based paracetamol medications are linked to acute kidney injury, which many of the children suffered.

The two ingredients are used in antifreeze, brake fluids and other industrial applications, but also as a cheaper alternative in some pharmaceutical products to glycerine, which is a solvent or thickening agent in many cough syrups. They can be toxic and can lead to acute kidney injury.

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Pipit Rismanto, a senior police official, told reporters authorities have found that CV Samudera Chemical sold “industrial-grade” EG and DEG as pharmaceutical-grade propylene glycol manufactured by Dow Chemical Thailand and supplied them to distributors of local drug-makers.

Police have arrested and charged officials at Samudera and its distributor CV Anugrah Perdana Gemilang. More suspects may be named as the investigation continues, Pipit said.

A cough medication is poured on Oct. 19, 2022. 

A cough medication is poured on Oct. 19, 2022. 
(REUTERS/Ajeng Dinar Ulfiana/Illustration)

Reuters could not immediately reach CV Samudera Chemical or its distributor for comment.

Riswan Sipayung, the president director of Dow Indonesia, said the company was “committed to working with the government, distributors and industry partners to do our part in mitigating the pervasive and urgent issue of counterfeiting and tackling this industry-wide problem with all stakeholders”.

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Last week, The World Health Organization called for “immediate and concerted action” to protect children from contaminated medicines after about 300 deaths in Gambia, Uzbekistan, and Indonesia linked to cough syrups last year.

Twenty-five Indonesian families of some of the children demanded restitution as a court this month started hearing their class-action lawsuit against government agencies and pharmaceutical firms.

Indonesia’s drugs regulator (BPOM) has said the spike in the cases occurred as several parties “exploited a gap in the safety guarantee system” and pharmaceutical companies did not sufficiently check the raw ingredients they used.

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